November 10, 2025
Asaase Radio
AfricaHeadlineHealthNewsscienceWorld

FDA approves world’s first biannual HIV prevention shot with 99.9% efficacy

In a historic move, the U.S. Food and Drug Administration (FDA) has approved the world’s first biannual injectable HIV prevention treatment, boasting a 99.9% success rate in major clinical trials. The approval marks a major leap forward in global HIV prevention efforts.

The injection, a twice-yearly pre-exposure prophylaxis (PrEP) treatment, offers a new level of convenience and effectiveness for individuals at high risk of HIV infection. Unlike daily oral PrEP pills, this long-acting injectable ensures six months of protection per dose, significantly improving adherence and privacy.

What Is It and How Does It Work?

The treatment, developed by leading pharmaceutical researchers and tested over multiple phases, works by releasing antiretroviral medication into the bloodstream gradually over six months. This prevents the HIV virus from establishing infection in the body.

According to FDA briefings and published trial data, the injection demonstrated near-total protection, especially among high-risk populations, including men who have sex with men, sex workers, and individuals in serodiscordant relationships.

Global Impact and Accessibility

Public health experts have hailed the development as a game-changer in ending the HIV epidemic. Health organizations are now calling for swift rollout globally, especially in regions with high HIV transmission rates.

Dr. Angela Miles, an infectious disease specialist, remarked:

“This innovation simplifies HIV prevention. For many, it will remove barriers related to daily medication — including stigma, forgetfulness, and accessibility.”

What’s Next?

While pricing and availability details are still being finalized, pharmaceutical stakeholders and global health agencies are expected to push for equitable access, especially in low-income countries. Discussions are underway with global NGOs, including UNAIDS and the WHO, to facilitate distribution partnerships.

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